Organosulfur Compounds
TARGETMOL CHEMICALS INC R-Sulforaphane 5MG
Also available in 1 mg, 2 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. (R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.
Medchemexpress LLC IL-17A modulator-3 | 2467732-95-0 | 99.37% | 639.80 | 25 MG
IL-17A modulator-3 (compound 253) is an IL-17A modulator that inhibits IL-17A/A with an IC50 value of less than 10 μM. This compound is suitable for research into inflammation, cancer, and autoimmune diseases.
- Inhibits IL-17A/A with an IC50 value of less than 10 μM
- Used for research on inflammation, cancer, and autoimmune diseases
- Molecular weight: 639.80
- Appearance: White to off-white solid
Medchemexpress LLC Kv3.1 modulator 2 | 99.8% | 437.88 | 50 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This modulator is suitable for laboratory research and studies involving Kv3.1 channels.
- Functions as a Kv3.1 channels modulator
- Has an EC50 value of 68 nM
Medchemexpress LLC YK-2168 | 2571068-74-9 | 98.1% | 315.80 | 25 MG
YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. It inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. This compound induces apoptosis in tumor cells, suppresses the expression of CDK9-regulated genes, and inhibits tumor growth in CDX mice models. It is suitable for cancer research, including leukemia.
- Potent and selective CDK9 inhibitor (IC50 = 5.9 nM)
- Inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain
- Induces apoptosis in tumor cells
- Suppresses expression of CDK9-regulated genes (e.g., MYC and Mcl1)
- Inhibits tumor growth in CDX mice models
- High selectivity over CDK1 and CDK2
- Does not inhibit hERG channel activity at concentrations up to 30 μM
- Demonstrates a good safety profile in animal models
Medchemexpress LLC (+)-LRH-1 modulator-1 | 99.38% | 464.66 | 1 MG
(+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1, which is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. It exhibits anti-inflammatory effects in intestinal organoids by inducing the anti-inflammatory cytokine IL-10 and reducing the inflammatory cytokines IL-1b and TNFa.
- Potent LRH-1 modulator/agonist
- Demonstrates anti-inflammatory effects
- Induces IL-10 cytokine
- Reduces IL-1b and TNFa cytokines
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 100 MG
GLP-1R modulator C16 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site with an EC50 of 8.43 ± 3.82 μM. It has a molecular weight of 408.89, appears as a solid with a white to off-white color, and is for research use only.
- Enhances GLP-1 binding to GLP-1R
- Allosteric modulator
- Molecular weight of 408.89
- Appears as a solid
- White to off-white color
- For research use only
Medchemexpress LLC Kv3.1 modulator 2 | 3035827-42-7 | 99.8% | 437.88 | 5 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This product is for research use only and is not sold to patients.
- Kv3.1 channels modulator
- EC50 value of 68 nM
eMolecules 67-68-5 | Dimethyl sulfoxide | Combi-Blocks | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Dimethyl sulfoxide | Combi-Blocks | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Medchemexpress LLC Ramelteon metabolite M-II-d3 | 1246812-22-5 | 99.8% | 278.36 g/mol | C16H18D3NO3 | 5 MG
Ramelteon metabolite M-II-d3 is the deuterium-labeled analog of the major human metabolite of ramelteon, provided as a high-purity reference standard intended for use as a tracer or internal standard in quantitative analytical methods. It is supplied as a solid suitable for laboratory analysis.
- Deuterium-labeled internal standard for quantitative analysis.
- High purity suitable for analytical work.
- Supplied as a white to off-white solid for ease of handling.
- Compatible with NMR, GC-MS, and LC-MS workflows.
- Molecular weight approximately 278.36 g/mol for accurate calculations.
Medchemexpress LLC GPR120 modulator 1 | 1050506-75-6 | 98.06% | C19H16ClNO4S | 50 MG
GPR120 modulator 1 is a G protein-coupled receptor 120 (GPR120) modulator, extracted from patent US8394841B2, compound example F1. It is intended for research use only and can be used for the study of diseases associated with abnormal or deregulated GPR120, such as diabetes.
- G protein-coupled receptor 120 (GPR120) modulator
- Extracted from patent US8394841B2, compound example F1
- Useful for research of diseases associated with abnormal or deregulated GPR120, such as diabetes
- For research use only
Sigma Aldrich Fine Chemicals Biosciences Guanidine thiocyanate for2.5KG
Guanidine thiocyanate for2.5KG
Cayman Chemical Sulindac sulfide
An active metabolite of sulindac; inhibits COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complications; inhibits colorectal cancer growth in vitro and in vivo
Cayman Chemical Sulindac sulfide
An active metabolite of sulindac; inhibits COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complications; inhibits colorectal cancer growth in vitro and in vivo